{ "_id": "6ab382963d719c1f84090596", "Package": "eadrm", "Title": "Fitting Dose-Response Models Using an Evolutionary Algorithm", "Version": "0.1.4", "Authors@R": "c(person(given = \"Eric\",\nfamily = \"Bair\",\nrole = c(\"aut\", \"cre\"),\nemail = \"eric.bair@sciome.com\"),\nperson(given = \"Jun\",\nfamily = \"Ma\",\nrole = \"aut\"))", "Description": "Fits dose-response models using an evolutionary algorithm\nto estimate the model parameters. The procedure currently can\nfit 3-parameter, 4-parameter, and 5-parameter log-logistic\nmodels as well as exponential models. Functions are also\nprovided to plot, make predictions, and calculate confidence\nintervals for the resulting models. For details see \"Nonlinear\nDose-response Modeling of High-Throughput Screening Data Using\nan Evolutionary Algorithm\", Ma, J., Bair, E., Motsinger-Reif,\nA.; Dose-Response 18(2):1559325820926734 (2020)\n.", "License": "GPL-3", "Encoding": "UTF-8", "LazyData": "true", "RoxygenNote": "7.2.0", "NeedsCompilation": "no", "Packaged": { "Date": "2026-09-23 07:12:10 UTC", "User": "root" }, "Author": "Eric Bair [aut, cre], Jun Ma [aut]", "Maintainer": "Eric Bair ", "Repository": "https://ericbair-sciome.r-universe.dev", "Date/Publication": "2022-05-29 04:40:06 UTC", "RemoteUrl": "https://github.com/cran/eadrm", "RemoteRef": "HEAD", "RemoteSha": "88645157fc36cab9d680e970df03b55b76202eb7", "_user": "ericbair-sciome", "_type": "src", "_file": "eadrm_0.1.4.tar.gz", "_fileid": "https://r2.ropensci.org/16bf5a31e541484bfb3cb9d490d8162c5d15b8f06dbe9edfd01b066ad3f04959", "_filesize": 114665, "_sha256": "16bf5a31e541484bfb3cb9d490d8162c5d15b8f06dbe9edfd01b066ad3f04959", "_expires": "2027-01-01T07:41:09.000Z", "_created": "2026-09-23T07:12:10.000Z", "_published": "2026-09-23T07:41:10.681Z", "_jobs": [ { "job": 107081759017, "time": 105, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "10736863835" }, { "job": 107081759077, "time": 102, "config": "linux-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "10736978225" }, { "job": 107081759083, "time": 159, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "10737338498" }, { "job": 107081759049, "time": 169, "config": "macos-release-arm64", "r": "4.6.1", "check": "OK", "artifact": "10737559670" }, { "job": 107081067219, "time": 148, "config": "source", "r": "4.6.1", "check": "OK", "artifact": "10735999969" }, { "job": 107081759005, "time": 87, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "10737510500" }, { "job": 107081759136, "time": 63, "config": "windows-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "10737350494" }, { "job": 107081759110, "time": 55, "config": "windows-oldrel-x86_64", "r": "4.5.3", "check": "OK", "artifact": "10737195310" }, { "job": 107081759207, "time": 45, "config": "windows-release-x86_64", "r": "4.6.1", "check": "OK", "artifact": "10736873675" } ], "_host": "GitHub-Actions", "_buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426", "_status": "success", "_upstream": "https://github.com/cran/eadrm", "_commit": { "id": "88645157fc36cab9d680e970df03b55b76202eb7", "author": "Eric Bair ", "committer": "cran-robot ", "message": "version 0.1.4\n", "time": 1653799206 }, "_maintainer": { "name": "Eric Bair", "email": "eric.bair@sciome.com", "login": "ericbair-sciome", "description": "", "uuid": 149633517 }, "_distro": "resolute", "_registered": true, "_dependencies": [ { "package": "R", "version": ">= 2.10.0", "role": "Depends" } ], "_owner": "cran", "_selfowned": true, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "ericbair-sciome", "count": 3, "uuid": 149633517 } ], "_userbio": { "uuid": 149633517, "type": "user", "name": "ericbair-sciome", "followers": 0 }, "_downloads": { "count": 243, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/eadrm" }, "_searchresults": 0, "_rbuild": "4.6.1", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/eadrm.html", "extra/manual.pdf", "extra/NEWS.html", "extra/NEWS.txt" ], "_realowner": "ericbair-sciome", "_cranurl": false, "_releases": [ { "version": "0.1.2", "date": "2020-04-28" }, { "version": "0.1.3", "date": "2020-07-05" }, { "version": "0.1.4", "date": "2022-05-29" } ], "_exports": [ "calc.ec", "calc.ed", "eadrm", "eadrm.ci" ], "_datasets": [ { "name": "CarboA", "title": "Example dose response dataset", "object": "CarboA", "class": [ "list" ], "fields": [], "table": true, "tojson": true } ], "_help": [ { "page": "calc.ec", "title": "Calculates EC50 (or some other specified EC value)", "topics": [ "calc.ec" ] }, { "page": "calc.ed", "title": "Finds the dose that corresponds to a particular level of the response", "topics": [ "calc.ed" ] }, { "page": "CarboA", "title": "Example dose response dataset", "topics": [ "CarboA" ] }, { "page": "eadrm", "title": "Fits a dose-response curve using an evolutionary algorithm", "topics": [ "eadrm" ] }, { "page": "eadrm.ci", "title": "Computes confidence intervals for an eadrm model fit", "topics": [ "eadrm.ci" ] }, { "page": "plot.eadrm", "title": "Plot an eadrm object", "topics": [ "plot.eadrm" ] }, { "page": "predict.eadrm", "title": "Makes predictions from an eadrm object", "topics": [ "predict.eadrm" ] } ], "_rundeps": [], "_score": 1, "_indexed": true, "_nocasepkg": "eadrm", "_universes": [ "ericbair-sciome" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "0.1.4", "date": "2026-09-23T07:13:59.000Z", "distro": "resolute", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/5e4c69f9f39878af24f57d6dfe5feb9f3e805899b7b88a19be7ba01f1103a489", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.6.1", "os": "linux", "version": "0.1.4", "date": "2026-09-23T07:13:58.000Z", "distro": "resolute", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/4b61c8e6a31dcde90b0681dfc0d0998e45458c166f2c11455ace9ac371e1d9fd", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.5.3", "os": "mac", "version": "0.1.4", "date": "2026-09-23T07:30:56.000Z", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/d429873f45e7dbe885773c10c653e199b7f43057dd6d69f95e86add254f4b7b1", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.6.1", "os": "mac", "version": "0.1.4", "date": "2026-09-23T07:39:55.000Z", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/190962495325a279441714bd83f6e95e7979e3af82dcc6ec500353937f87b6b8", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.6.0", "os": "wasm", "version": "0.1.4", "date": "2026-09-23T07:13:52.000Z", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/e4278720fe76dcccb4644fc5e2e65e161cd3174af195108138d783f88de1cbd4", "status": "success", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.7.0", "os": "win", "version": "0.1.4", "date": "2026-09-23T07:13:14.000Z", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/4e9f78ebabb60f63a1a4ecd13b174a7d3b6c1b8625b88d53d331dfbffd396ed3", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.5.3", "os": "win", "version": "0.1.4", "date": "2026-09-23T07:13:04.000Z", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/8cb54bdbe3808242ac6d659df0d93a67e335d56d1b7858b748f42b8fe9e37623", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" }, { "r": "4.6.1", "os": "win", "version": "0.1.4", "date": "2026-09-23T07:12:59.000Z", "commit": "88645157fc36cab9d680e970df03b55b76202eb7", "fileid": "https://r2.ropensci.org/0e2ec1767f77644ef58ffdce45502250eb30985c5783f9002e1fdf1de81b0213", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/ericbair-sciome/actions/runs/35830230426" } ] }